News

Check here regularly for updates on activities within the Program and its projects.

Pacylex Pharmaceuticals Begins Phase I Clinical Trial (Sept. 14, 2021).

 

Local startup Pacylex Pharmaceuticals Inc. today initiated the PCLX-001-01 Phase I clinical trial at the Cross Cancer Institute in Edmonton.  The focus of the trial will be the safety and tolerability of its lead anti-cancer drug, PCLX-001, and determination of an appropriate dose for future Phase II and III studies.  In the trial, PCLX-001 will be tested in a limited number of patients with lymphoma or solid tumour malignancies. 

 

Pacylex was formed around discoveries in the University of Alberta lab of Dr. Luc Berthiaume. The trial represents a successful translation of discovery research to human clinical testing, and highlights the role of the PP1P: to accelerate Alberta-based innovations to the clinic. This endeavour brings a novel new drug candidate to first-in-human testing.  For more information, please refer to the links below.

 

Pacylex Pharmaceuticals, Inc.

Find a Clinical Trial (albertacancerclinicaltrials.ca)

Phase I Trial of PCLX-001 in B-cell Non-Hodgkin Lymphoma and Advanced Solid Malignancies - Full Text View - ClinicalTrials.gov  

PharmaMatrix Holdings Ltd Begins Phase I Clinical Trial (September 29, 2021).

 

Local startup PharmaMatrix Holdings Ltd. today initiated the PMH-001 Phase I clinical trial at the Cross Cancer Institute in Edmonton to test its lead anti-cancer drug, CCI-001.  The focus of the trial will be the safety and tolerability of CCI-001, and determination of an appropriate dose for future Phase II and III studies.  In the trial, CCI-001 will be tested in a limited number of patients with recurrent and/or metastatic solid tumours. 

 

The CCI-001 drug candidate is the product of computational modelling by the University of Alberta lab of Dr. Jack Tuszynski.  The trial is another example of successful translation of Alberta-based research, bringing a novel new drug candidate to first-in-human testing.  For more information, please refer to the links below.

 

Find a Clinical Trial (albertacancerclinicaltrials.ca)

A Study of CCI-001 in Patients With Recurrent and/or Metastatic Solid Tumours - Full Text View - ClinicalTrials.gov

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